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IQGAP1 Is Involved in Enhanced Aggressive Behavior of Epithelial Ovarian Cancer Stem Cell-Like Cells During Differentiation

BACKGROUND: Wide metastasis is one of characteristics of ovarian cancer. Cancer stem cells, as a source in cancer invasion and metastasis, possess powerful potential of differentiation. Scaffolding IQ domain GTPase-activating protein 1 (IQGAP1) plays a key role in the invasion and metastasis of canc...

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Detalles Bibliográficos
Autores principales: Huang, Lu, Xu, Shanshan, Hu, Dongxiao, Lu, Weiguo, Xie, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406980/
https://www.ncbi.nlm.nih.gov/pubmed/25675045
http://dx.doi.org/10.1097/IGC.0000000000000394