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Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a devastating neurodegenerative disorder characterized by the progressive loss of spinal motor neurons. While the aetiological mechanisms underlying the disease remain poorly understood, oxidative stress is a central component of amyotrophic lateral sclerosis and con...

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Detalles Bibliográficos
Autores principales: Liu, Kevin X., Edwards, Benjamin, Lee, Sheena, Finelli, Mattéa J., Davies, Ben, Davies, Kay E., Oliver, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407188/
https://www.ncbi.nlm.nih.gov/pubmed/25753484
http://dx.doi.org/10.1093/brain/awv039