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Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis is a devastating neurodegenerative disorder characterized by the progressive loss of spinal motor neurons. While the aetiological mechanisms underlying the disease remain poorly understood, oxidative stress is a central component of amyotrophic lateral sclerosis and con...
Autores principales: | Liu, Kevin X., Edwards, Benjamin, Lee, Sheena, Finelli, Mattéa J., Davies, Ben, Davies, Kay E., Oliver, Peter L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407188/ https://www.ncbi.nlm.nih.gov/pubmed/25753484 http://dx.doi.org/10.1093/brain/awv039 |
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