Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse

The completion of genome duplication during the cell cycle is threatened by the presence of replication fork barriers (RFBs). Following collision with a RFB, replication proteins can dissociate from the stalled fork (fork collapse) rendering it incapable of further DNA synthesis unless recombination...

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Detalles Bibliográficos
Autores principales: Nguyen, Michael O, Jalan, Manisha, Morrow, Carl A, Osman, Fekret, Whitby, Matthew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407270/
https://www.ncbi.nlm.nih.gov/pubmed/25806683
http://dx.doi.org/10.7554/eLife.04539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407270/
https://www.ncbi.nlm.nih.gov/pubmed/25806683
http://dx.doi.org/10.7554/eLife.04539

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