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Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse
The completion of genome duplication during the cell cycle is threatened by the presence of replication fork barriers (RFBs). Following collision with a RFB, replication proteins can dissociate from the stalled fork (fork collapse) rendering it incapable of further DNA synthesis unless recombination...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407270/ https://www.ncbi.nlm.nih.gov/pubmed/25806683 http://dx.doi.org/10.7554/eLife.04539 |