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A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

BACKGROUND: Obesity is strongly associated with major depressive disorder (MDD) and various other diseases. Genome-wide association studies have identified multiple risk loci robustly associated with body mass index (BMI). In this study, we aimed to investigate whether a genetic risk score (GRS) com...

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Detalles Bibliográficos
Autores principales: Hung, Chi-Fa, Breen, Gerome, Czamara, Darina, Corre, Tanguy, Wolf, Christiane, Kloiber, Stefan, Bergmann, Sven, Craddock, Nick, Gill, Michael, Holsboer, Florian, Jones, Lisa, Jones, Ian, Korszun, Ania, Kutalik, Zoltan, Lucae, Susanne, Maier, Wolfgang, Mors, Ole, Owen, Michael J, Rice, John, Rietschel, Marcella, Uher, Rudolf, Vollenweider, Peter, Waeber, Gerard, Craig, Ian W, Farmer, Anne E, Lewis, Cathryn M, Müller-Myhsok, Bertram, Preisig, Martin, McGuffin, Peter, Rivera, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407390/
https://www.ncbi.nlm.nih.gov/pubmed/25903154
http://dx.doi.org/10.1186/s12916-015-0334-3