A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell lines

INTRODUCTION: Research involving antimitotic compounds identified 2-methoxyestradiol (2ME2), as a promising anticancer endogenous metabolite. Owing to its low bioavailability, several in silico-designed 2ME2 analogues were synthesized. Structure-activity relationship studies indicated that an alread...

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Detalles Bibliográficos
Autores principales: Visagie, Michelle Helen, Birkholtz, Lyn-Marie, Joubert, Anna Margaretha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407428/
https://www.ncbi.nlm.nih.gov/pubmed/25908963
http://dx.doi.org/10.1186/s13578-015-0010-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407428/
https://www.ncbi.nlm.nih.gov/pubmed/25908963
http://dx.doi.org/10.1186/s13578-015-0010-5

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