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A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell lines
INTRODUCTION: Research involving antimitotic compounds identified 2-methoxyestradiol (2ME2), as a promising anticancer endogenous metabolite. Owing to its low bioavailability, several in silico-designed 2ME2 analogues were synthesized. Structure-activity relationship studies indicated that an alread...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407428/ https://www.ncbi.nlm.nih.gov/pubmed/25908963 http://dx.doi.org/10.1186/s13578-015-0010-5 |