Regulation of System x (c) (−) by Pharmacological Manipulation of Cellular Thiols

The cystine/glutamate exchanger (system x(c) (−)) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, system x(c) (−) can potentially cause excitotoxicity. However, through providing cystine to the cell, it regulates the levels of cellular glutathione (...

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Detalles Bibliográficos
Autores principales: Albano, Rebecca, Raddatz, Nicholas J., Hjelmhaug, Julie, Baker, David A., Lobner, Doug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407525/
https://www.ncbi.nlm.nih.gov/pubmed/25949770
http://dx.doi.org/10.1155/2015/269371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407525/
https://www.ncbi.nlm.nih.gov/pubmed/25949770
http://dx.doi.org/10.1155/2015/269371

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