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The Ensembl Regulatory Build

Most genomic variants associated with phenotypic traits or disease do not fall within gene coding regions, but in regulatory regions, rendering their interpretation difficult. We collected public data on epigenetic marks and transcription factor binding in human cell types and used it to construct a...

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Detalles Bibliográficos
Autores principales: Zerbino, Daniel R, Wilder, Steven P, Johnson, Nathan, Juettemann, Thomas, Flicek, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407537/
https://www.ncbi.nlm.nih.gov/pubmed/25887522
http://dx.doi.org/10.1186/s13059-015-0621-5