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Distinct effects of ubiquitin overexpression on NMJ structure and motor performance in mice expressing catalytically inactive USP14

Ubiquitin-specific protease 14 (USP14) is a major deubiquitinating enzyme and a key determinant of neuromuscular junction (NMJ) structure and function. We have previously reported dramatic ubiquitin depletion in the nervous systems of the USP14-deficient ataxia (ax(J)) mice and demonstrated that tra...

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Detalles Bibliográficos
Autores principales:	Vaden, Jada H., Watson, Jennifer A., Howard, Alan D., Chen, Ping-Chung, Wilson, Julie A., Wilson, Scott M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407586/ https://www.ncbi.nlm.nih.gov/pubmed/25954152 http://dx.doi.org/10.3389/fnmol.2015.00011

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