Sitagliptin attenuates sympathetic innervation via modulating reactive oxygen species and interstitial adenosine in infarcted rat hearts

We investigated whether sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, attenuates arrhythmias through inhibiting nerve growth factor (NGF) expression in post-infarcted normoglycemic rats, focusing on adenosine and reactive oxygen species production. DPP-4 bound adenosine deaminase has been...

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Detalles Bibliográficos
Autores principales: Lee, Tsung-Ming, Chen, Wei-Ting, Yang, Chen-Chia, Lin, Shinn-Zong, Chang, Nen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407589/
https://www.ncbi.nlm.nih.gov/pubmed/25388908
http://dx.doi.org/10.1111/jcmm.12465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407589/
https://www.ncbi.nlm.nih.gov/pubmed/25388908
http://dx.doi.org/10.1111/jcmm.12465

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