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Sitagliptin attenuates sympathetic innervation via modulating reactive oxygen species and interstitial adenosine in infarcted rat hearts
We investigated whether sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, attenuates arrhythmias through inhibiting nerve growth factor (NGF) expression in post-infarcted normoglycemic rats, focusing on adenosine and reactive oxygen species production. DPP-4 bound adenosine deaminase has been...
Autores principales: | Lee, Tsung-Ming, Chen, Wei-Ting, Yang, Chen-Chia, Lin, Shinn-Zong, Chang, Nen-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407589/ https://www.ncbi.nlm.nih.gov/pubmed/25388908 http://dx.doi.org/10.1111/jcmm.12465 |
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