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MicroRNA-30d and microRNA-181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse

The balanced turnover of collagen is necessary to maintain the mechanical strength of pelvic supportive connective tissues. Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosacral ligaments (USLs), and the deficient HOXA11 signalling m...

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Detalles Bibliográficos
Autores principales: Jeon, Myung Jae, Kim, Eun Jae, Lee, Maria, Kim, Hoguen, Choi, Jong Rak, Chae, Hee Dong, Moon, Yeo Jung, Kim, Sei Kwang, Bai, Sang Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407598/
https://www.ncbi.nlm.nih.gov/pubmed/25630974
http://dx.doi.org/10.1111/jcmm.12448