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A novel therapeutic effect of statins on nephrogenic diabetes insipidus

Statins competitively inhibit hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase, resulting in reduced plasma total and low-density lipoprotein cholesterol levels. Recently, it has been shown that statins exert additional ‘pleiotropic’ effects by increasing expression levels of the membrane wat...

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Detalles Bibliográficos
Autores principales: Bonfrate, Leonilde, Procino, Giuseppe, Wang, David Q-H, Svelto, Maria, Portincasa, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407600/
https://www.ncbi.nlm.nih.gov/pubmed/25594563
http://dx.doi.org/10.1111/jcmm.12422