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A novel therapeutic effect of statins on nephrogenic diabetes insipidus
Statins competitively inhibit hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase, resulting in reduced plasma total and low-density lipoprotein cholesterol levels. Recently, it has been shown that statins exert additional ‘pleiotropic’ effects by increasing expression levels of the membrane wat...
Autores principales: | Bonfrate, Leonilde, Procino, Giuseppe, Wang, David Q-H, Svelto, Maria, Portincasa, Piero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407600/ https://www.ncbi.nlm.nih.gov/pubmed/25594563 http://dx.doi.org/10.1111/jcmm.12422 |
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