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Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow-derived cells

To assess effects of epidermal growth factor (EGF) and pegylated granulocyte colony-stimulating factor (P-GCSF; pegfilgrastim) administration on the cellular origin of renal tubular epithelium regenerating after acute kidney injury initiated by mercuric chloride (HgCl(2)). Female mice were irradiate...

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Detalles Bibliográficos
Autores principales: Yen, Tzung-Hai, Alison, Malcolm R, Goodlad, Robert A, Otto, William R, Jeffery, Rosemary, Cook, H Terence, Wright, Nicholas A, Poulsom, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407604/
https://www.ncbi.nlm.nih.gov/pubmed/25389045
http://dx.doi.org/10.1111/jcmm.12478