PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulation

The platelet-derived growth factor (PDGF) signalling pathway has been reported to play an important role in human cancers by modulating autocrine and paracrine processes such as tumour growth, metastasis and angiogenesis. Several clinical trials document the benefits of targeting this pathway; howev...

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Detalles Bibliográficos
Autores principales: Tudoran, Oana Mihaela, Soritau, Olga, Balacescu, Loredana, Pop, Laura, Meurice, Guillaume, Visan, Simona, Lindberg, Staffan, Eniu, Alexandru, Langel, Ulo, Balacescu, Ovidiu, Berindan-Neagoe, Ioana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407607/
https://www.ncbi.nlm.nih.gov/pubmed/25311137
http://dx.doi.org/10.1111/jcmm.12449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407607/
https://www.ncbi.nlm.nih.gov/pubmed/25311137
http://dx.doi.org/10.1111/jcmm.12449

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