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PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulation
The platelet-derived growth factor (PDGF) signalling pathway has been reported to play an important role in human cancers by modulating autocrine and paracrine processes such as tumour growth, metastasis and angiogenesis. Several clinical trials document the benefits of targeting this pathway; howev...
Autores principales: | Tudoran, Oana Mihaela, Soritau, Olga, Balacescu, Loredana, Pop, Laura, Meurice, Guillaume, Visan, Simona, Lindberg, Staffan, Eniu, Alexandru, Langel, Ulo, Balacescu, Ovidiu, Berindan-Neagoe, Ioana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407607/ https://www.ncbi.nlm.nih.gov/pubmed/25311137 http://dx.doi.org/10.1111/jcmm.12449 |
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