Combined comparative genomic hybridization and transcriptomic analyses of ovarian granulosa cell tumors point to novel candidate driver genes

BACKGROUND: Ovarian granulosa cell tumors (GCTs) are the most frequent sex cord-stromal tumors. Several studies have shown that a somatic mutation leading to a C134W substitution in the transcription factor FOXL2 appears in more than 95% of adult-type GCTs. Its pervasive presence suggests that FOXL2...

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Detalles Bibliográficos
Autores principales: Caburet, Sandrine, Anttonen, Mikko, Todeschini, Anne-Laure, Unkila-Kallio, Leila, Mestivier, Denis, Butzow, Ralf, Veitia, Reiner A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407711/
https://www.ncbi.nlm.nih.gov/pubmed/25884336
http://dx.doi.org/10.1186/s12885-015-1283-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407711/
https://www.ncbi.nlm.nih.gov/pubmed/25884336
http://dx.doi.org/10.1186/s12885-015-1283-0

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