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Combined comparative genomic hybridization and transcriptomic analyses of ovarian granulosa cell tumors point to novel candidate driver genes

BACKGROUND: Ovarian granulosa cell tumors (GCTs) are the most frequent sex cord-stromal tumors. Several studies have shown that a somatic mutation leading to a C134W substitution in the transcription factor FOXL2 appears in more than 95% of adult-type GCTs. Its pervasive presence suggests that FOXL2...

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Detalles Bibliográficos
Autores principales:	Caburet, Sandrine, Anttonen, Mikko, Todeschini, Anne-Laure, Unkila-Kallio, Leila, Mestivier, Denis, Butzow, Ralf, Veitia, Reiner A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407711/ https://www.ncbi.nlm.nih.gov/pubmed/25884336 http://dx.doi.org/10.1186/s12885-015-1283-0

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