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Mechanistic Insights into Elastin Degradation by Pseudolysin, the Major Virulence Factor of the Opportunistic Pathogen Pseudomonas aeruginosa

Pseudolysin is the most abundant protease secreted by Pseudomonas aeruginosa and is the major extracellular virulence factor of this opportunistic human pathogen. Pseudolysin destroys human tissues by solubilizing elastin. However, the mechanisms by which pseudolysin binds to and degrades elastin re...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Zhao, Hui-Lin, Ran, Li-Yuan, Li, Chun-Yang, Zhang, Xi-Ying, Su, Hai-Nan, Shi, Mei, Zhou, Bai-Cheng, Chen, Xiu-Lan, Zhang, Yu-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407726/
https://www.ncbi.nlm.nih.gov/pubmed/25905792
http://dx.doi.org/10.1038/srep09936