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Amylin-Induced Central IL-6 Production Enhances Ventromedial Hypothalamic Leptin Signaling
Amylin acts acutely via the area postrema to reduce food intake and body weight, but it also interacts with leptin over longer periods of time, possibly via the ventromedial hypothalamus (VMH), to increase leptin signaling and phosphorylation of STAT3. We postulated that amylin enhances VMH leptin s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407855/ https://www.ncbi.nlm.nih.gov/pubmed/25409701 http://dx.doi.org/10.2337/db14-0645 |