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Amylin-Induced Central IL-6 Production Enhances Ventromedial Hypothalamic Leptin Signaling

Amylin acts acutely via the area postrema to reduce food intake and body weight, but it also interacts with leptin over longer periods of time, possibly via the ventromedial hypothalamus (VMH), to increase leptin signaling and phosphorylation of STAT3. We postulated that amylin enhances VMH leptin s...

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Detalles Bibliográficos
Autores principales:	Le Foll, Christelle, Johnson, Miranda D., Dunn-Meynell, Ambrose A., Boyle, Christina N., Lutz, Thomas A., Levin, Barry E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407855/ https://www.ncbi.nlm.nih.gov/pubmed/25409701 http://dx.doi.org/10.2337/db14-0645

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