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Oxidants Induce a Corticosteroid-Insensitive Phosphorylation of Histone 3 at Serine 10 in Monocytes

Oxidative stress enhances inflammation and reduces the effectiveness of corticosteroids, but the inflammatory signalling pathways induced by oxidants remain ill-defined. Phosphorylation of histone 3 at serine 10 (H3-Pser10) marks out a subset of inflammatory genes for transcription, several of which...

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Detalles Bibliográficos
Autores principales: Marwick, John A., Tudor, Corina, Khorasani, Nadia, Michaeloudes, Charalambos, Bhavsar, Pankaj K., Chung, Kian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407905/
https://www.ncbi.nlm.nih.gov/pubmed/25905622
http://dx.doi.org/10.1371/journal.pone.0124961