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The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes

BACKGROUND & AIMS: The organic solute transporters alpha and beta (OSTα-OSTβ) form a heterodimeric transporter located at the basolateral membrane of intestinal epithelial cells and hepatocytes. Liver injury caused by ischaemia-reperfusion, cancer, inflammation or cholestasis can induce a state...

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Detalles Bibliográficos
Autores principales: Schaffner, Carlos A, Mwinyi, Jessica, Gai, Zhibo, Thasler, Wolfgang E, Eloranta, Jyrki J, Kullak-Ublick, Gerd A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407926/
https://www.ncbi.nlm.nih.gov/pubmed/24703425
http://dx.doi.org/10.1111/liv.12558