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Dual miRNA Targeting Restricts Host Range and Attenuates Neurovirulence of Flaviviruses

Mosquito-borne flaviviruses are among the most significant arboviral pathogens worldwide. Vaccinations and mosquito population control programs remain the most reliable means for flavivirus disease prevention, and live attenuated viruses remain one of the most attractive flavivirus vaccine platforms...

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Detalles Bibliográficos
Autores principales: Tsetsarkin, Konstantin A., Liu, Guangping, Kenney, Heather, Bustos-Arriaga, Jose, Hanson, Christopher T., Whitehead, Stephen S., Pletnev, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408003/
https://www.ncbi.nlm.nih.gov/pubmed/25906260
http://dx.doi.org/10.1371/journal.ppat.1004852