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KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair

Homologous recombination and non-homologous end joining are two major DNA double-strand-break repair pathways. While HR-mediated repair requires a homologous sequence as the guiding template to restore the damage site precisely, NHEJ-mediated repair ligates the DNA lesion directly and increases the...

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Detalles Bibliográficos
Autores principales:	Lin, Yi-Hui, Yuan, Jian, Pei, Huadong, Liu, Tongzheng, Ann, David K., Lou, Zhenkun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408008/ https://www.ncbi.nlm.nih.gov/pubmed/25905708 http://dx.doi.org/10.1371/journal.pone.0123935

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