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Identification of Broad-Genotype HPV L2 Neutralization Site for Pan-HPV Vaccine Development by a Cross-Neutralizing Antibody

Human Papillomavirus (HPV), a non-enveloped, double-stranded DNA virus, is responsible for 5% of human cancers. The HPV capsid consists of major and minor structural proteins, L1 and L2. L1 proteins form an icosahedral shell with building blocks of the pentameric capsomere, and one L2 molecule exten...

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Detalles Bibliográficos
Autores principales: Wang, Daning, Li, Zhihai, Xiao, Jieqiong, Wang, Junqi, Zhang, Li, Liu, Yajing, Fan, Fei, Xin, Lu, Wei, Minxi, Kong, Zhibo, Yu, Hai, Gu, Ying, Zhang, Jun, Li, Shaowei, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408011/
https://www.ncbi.nlm.nih.gov/pubmed/25905781
http://dx.doi.org/10.1371/journal.pone.0123944