The Pif1 Helicase, a Negative Regulator of Telomerase, Acts Preferentially at Long Telomeres

Telomerase, the enzyme that maintains telomeres, preferentially lengthens short telomeres. The S. cerevisiae Pif1 DNA helicase inhibits both telomerase-mediated telomere lengthening and de novo telomere addition at double strand breaks (DSB). Here, we report that the association of the telomerase su...

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Detalles Bibliográficos
Autores principales: Phillips, Jane A., Chan, Angela, Paeschke, Katrin, Zakian, Virginia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408051/
https://www.ncbi.nlm.nih.gov/pubmed/25906395
http://dx.doi.org/10.1371/journal.pgen.1005186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408051/
https://www.ncbi.nlm.nih.gov/pubmed/25906395
http://dx.doi.org/10.1371/journal.pgen.1005186

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