Hyperplastic Growth of Pulmonary Artery Smooth Muscle Cells from Subjects with Pulmonary Arterial Hypertension Is Activated through JNK and p38 MAPK

Smooth muscle in the pulmonary artery of PAH subjects, both idiopathic and hereditary, is characterized by hyperplasia. Smooth muscle cells (HPASMC) isolated from subjects with or without PAH retain their in vivo phenotype as illustrated by their expression of alpha-smooth muscle actin and expressio...

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Detalles Bibliográficos
Autores principales: Wilson, Jamie L., Yu, Jun, Taylor, Linda, Polgar, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408087/
https://www.ncbi.nlm.nih.gov/pubmed/25905460
http://dx.doi.org/10.1371/journal.pone.0123662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408087/
https://www.ncbi.nlm.nih.gov/pubmed/25905460
http://dx.doi.org/10.1371/journal.pone.0123662

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