Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization

Skin permeability is widely considered to be mechanistically implicated in chemically-induced skin sensitization. Although many chemicals have been identified as skin sensitizers, there have been very few reports analyzing the relationships between molecular structure and skin permeability of sensit...

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Detalles Bibliográficos
Autores principales: Alves, Vinicius M., Muratov, Eugene, Fourches, Denis, Strickland, Judy, Kleinstreuer, Nicole, Andrade, Carolina H., Tropsha, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408226/
https://www.ncbi.nlm.nih.gov/pubmed/25560673
http://dx.doi.org/10.1016/j.taap.2014.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408226/
https://www.ncbi.nlm.nih.gov/pubmed/25560673
http://dx.doi.org/10.1016/j.taap.2014.12.013

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