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Metal-deficient SOD1 in amyotrophic lateral sclerosis

Mutations to the ubiquitous antioxidant enzyme Cu/Zn superoxide dismutase (SOD1) were the first established genetic cause of the fatal, adult-onset neurodegenerative disease amyotrophic lateral sclerosis (ALS). It is widely accepted that these mutations do not cause ALS via a loss of antioxidant fun...

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Detalles Bibliográficos
Autores principales: Hilton, James B., White, Anthony R., Crouch, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408375/
https://www.ncbi.nlm.nih.gov/pubmed/25754173
http://dx.doi.org/10.1007/s00109-015-1273-3