FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis

INTRODUCTION: FUS/TLS is an RNA-binding protein whose genetic mutations or pathological inclusions are associated with neurological diseases including amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration, and essential tremor (ET). It is unclear whether their pathogenesis is mediat...

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Detalles Bibliográficos
Autores principales: Kino, Yoshihiro, Washizu, Chika, Kurosawa, Masaru, Yamada, Mizuki, Miyazaki, Haruko, Akagi, Takumi, Hashikawa, Tsutomu, Doi, Hiroshi, Takumi, Toru, Hicks, Geoffrey G, Hattori, Nobutaka, Shimogori, Tomomi, Nukina, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408580/
https://www.ncbi.nlm.nih.gov/pubmed/25907258
http://dx.doi.org/10.1186/s40478-015-0202-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408580/
https://www.ncbi.nlm.nih.gov/pubmed/25907258
http://dx.doi.org/10.1186/s40478-015-0202-6

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