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Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level
BACKGROUND: The methylotrophic, Crabtree-negative yeast Pichia pastoris is widely used as a heterologous protein production host. Strong inducible promoters derived from methanol utilization genes or constitutive glycolytic promoters are typically used to drive gene expression. Notably, genes involv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408588/ https://www.ncbi.nlm.nih.gov/pubmed/25887254 http://dx.doi.org/10.1186/s12864-015-1393-8 |