Intrahippocampal glutamine administration inhibits mTORC1 signaling and impairs long-term memory

The mechanistic Target of Rapamycin Complex 1 (mTORC1), a key regulator of protein synthesis and cellular growth, is also required for long-term memory formation. Stimulation of mTORC1 signaling is known to be dependent on the availability of energy and growth factors, as well as the presence of ami...

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Detalles Bibliográficos
Autores principales: Rozas, Natalia S., Redell, John B., Pita-Almenar, Juan D., Mckenna, James, Moore, Anthony N., Gambello, Michael J., Dash, Pramod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408772/
https://www.ncbi.nlm.nih.gov/pubmed/25878136
http://dx.doi.org/10.1101/lm.038265.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408772/
https://www.ncbi.nlm.nih.gov/pubmed/25878136
http://dx.doi.org/10.1101/lm.038265.115

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