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SHAPE Selection (SHAPES) enrich for RNA structure signal in SHAPE sequencing-based probing data
Selective 2′ Hydroxyl Acylation analyzed by Primer Extension (SHAPE) is an accurate method for probing of RNA secondary structure. In existing SHAPE methods, the SHAPE probing signal is normalized to a no-reagent control to correct for the background caused by premature termination of the reverse tr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408784/ https://www.ncbi.nlm.nih.gov/pubmed/25805860 http://dx.doi.org/10.1261/rna.047068.114 |