Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists

Piwi-interacting RNAs (piRNAs) guide Piwi argonautes to their transposon targets for silencing. The highly conserved protein Maelstrom is linked to both piRNA biogenesis and effector roles in this pathway. One defining feature of Maelstrom is the predicted MAEL domain of unknown molecular function....

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Ming, Campbell, Edgar, Pandey, Radha Raman, Yang, Zhaolin, McCarthy, Andrew A., Pillai, Ramesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408791/
https://www.ncbi.nlm.nih.gov/pubmed/25778731
http://dx.doi.org/10.1261/rna.049437.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408791/
https://www.ncbi.nlm.nih.gov/pubmed/25778731
http://dx.doi.org/10.1261/rna.049437.114

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