Cargando…

Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation

Insulin-like growth factor (IGF) signaling is fundamental for growth and survival. A large body of evidence (laboratory, epidemiological, and clinical) implicates the exploitation of this pathway in cancer. Up to 50% of breast tumors express the activated form of the type 1 insulin-like growth facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Farabaugh, Susan M., Boone, David N., Lee, Adrian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408912/
https://www.ncbi.nlm.nih.gov/pubmed/25964777
http://dx.doi.org/10.3389/fendo.2015.00059