Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment

Familial Mediterranean fever is an autosomal recessive autoinflammatory disorder mainly affecting Mediterranean populations, which is associated with mutations of the MEFV gene that encodes pyrin. Functional studies suggest that pyrin is implicated in the maturation and secretion of interleukin-1 (I...

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Detalles Bibliográficos
Autores principales: Alpa, Mirella, Roccatello, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408939/
https://www.ncbi.nlm.nih.gov/pubmed/25945034
http://dx.doi.org/10.2147/DDDT.S69117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408939/
https://www.ncbi.nlm.nih.gov/pubmed/25945034
http://dx.doi.org/10.2147/DDDT.S69117

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