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Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment
Familial Mediterranean fever is an autosomal recessive autoinflammatory disorder mainly affecting Mediterranean populations, which is associated with mutations of the MEFV gene that encodes pyrin. Functional studies suggest that pyrin is implicated in the maturation and secretion of interleukin-1 (I...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408939/ https://www.ncbi.nlm.nih.gov/pubmed/25945034 http://dx.doi.org/10.2147/DDDT.S69117 |