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Ddx1 knockout results in transgenerational wild-type lethality in mice

DEAD box 1 (DDX1) is a member of the DEAD box family of RNA helicases which are involved in all aspects of RNA metabolism. DDX1 has been implicated in a variety of biological processes, including 3’-end processing of mRNA, DNA repair, microRNA processing, tRNA maturation and mRNA transport. To study...

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Detalles Bibliográficos
Autores principales: Hildebrandt, Matthew R., Germain, Devon R., Monckton, Elizabeth A., Brun, Miranda, Godbout, Roseline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408975/
https://www.ncbi.nlm.nih.gov/pubmed/25909345
http://dx.doi.org/10.1038/srep09829