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Sources of dynamic variability in NF-κB signal transduction: A mechanistic model

The transcription factor NF-κB (p65/p50) plays a central role in the coordination of cellular responses by activating the transcription of numerous target genes. The precise role of the dynamics of NF-κB signalling in regulating gene expression is still an open question. Here, we show that besides e...

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Detalles Bibliográficos
Autores principales: Mothes, Janina, Busse, Dorothea, Kofahl, Bente, Wolf, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409097/
https://www.ncbi.nlm.nih.gov/pubmed/25640005
http://dx.doi.org/10.1002/bies.201400113