Cargando…

The Immune Adaptor ADAP Regulates Reciprocal TGF-β1-Integrin Crosstalk to Protect from Influenza Virus Infection

Highly pathogenic avian influenza virus (HPAI, such as H5N1) infection causes severe cytokine storm and fatal respiratory immunopathogenesis in human and animal. Although TGF-β1 and the integrin CD103 in CD8(+) T cells play protective roles in H5N1 virus infection, it is not fully understood which k...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chunyang, Jiao, Shaozhuo, Wang, Guojun, Gao, Yunzhen, Liu, Chang, He, Xijun, Zhang, Chi, Xiao, Jun, Li, Weiyun, Zhang, Guoquan, Wei, Bin, Chen, Hualan, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409120/
https://www.ncbi.nlm.nih.gov/pubmed/25909459
http://dx.doi.org/10.1371/journal.ppat.1004824