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Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice

Insulin resistance (IR) underlies metabolic disease. Visceral, but not subcutaneous, white adipose tissue (WAT) has been linked to the development of IR, potentially due to differences in regulatory protein abundance. Here we investigate how protein levels are changed in IR in different WAT depots b...

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Detalles Bibliográficos
Autores principales: Ota, Asuka, Kovary, Kyle M., Wu, Olivia H., Ahrends, Robert, Shen, Wen-Jun, Costa, Maria J., Feldman, Brian J., Kraemer, Fredric B., Teruel, Mary N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409283/
https://www.ncbi.nlm.nih.gov/pubmed/25840986
http://dx.doi.org/10.1194/jlr.D056317