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Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

The ability of HDL to support macrophage cholesterol efflux is an integral part of its atheroprotective action. Augmenting this ability, especially when HDL cholesterol efflux capacity from macrophages is poor, represents a promising therapeutic strategy. One approach to enhancing macrophage cholest...

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Detalles Bibliográficos
Autores principales: Luthi, Andrea J., Lyssenko, Nicholas N., Quach, Duyen, McMahon, Kaylin M., Millar, John S., Vickers, Kasey C., Rader, Daniel J., Phillips, Michael C., Mirkin, Chad A., Thaxton, C. Shad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409287/
https://www.ncbi.nlm.nih.gov/pubmed/25652088
http://dx.doi.org/10.1194/jlr.M054635