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BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses

Endoglin is a type III TGFβ auxiliary receptor that is upregulated in endothelial cells during angiogenesis and, when mutated in humans, results in the vascular disease hereditary hemorrhagic telangiectasia (HHT). Though endoglin has been implicated in cell adhesion, the underlying molecular mechani...

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Detalles Bibliográficos
Autores principales: Young, Kira, Tweedie, Eric, Conley, Barbara, Ames, Jacquelyn, FitzSimons, MaryLynn, Brooks, Peter, Liaw, Lucy, Vary, Calvin P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409298/
https://www.ncbi.nlm.nih.gov/pubmed/25909848
http://dx.doi.org/10.1371/journal.pone.0122892