IL-4 Up-Regulates MiR-21 and the MiRNAs Hosted in the CLCN5 Gene in Chronic Lymphocytic Leukemia

Interleukin 4 (IL-4) induces B-cell differentiation and survival of chronic lymphocytic leukemia (CLL) cells. MicroRNAs (miRNAs) regulate mRNA and protein expression, and several miRNAs, deregulated in CLL, might play roles as oncogenes or tumor suppressors. We have studied the miRNA profile of CLL,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz-Lafuente, Natalia, Alcaraz-García, María-José, Sebastián-Ruiz, Silvia, García-Serna, Azahara-María, Gómez-Espuch, Joaquín, Moraleda, José-María, Minguela, Alfredo, García-Alonso, Ana-María, Parrado, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409305/
https://www.ncbi.nlm.nih.gov/pubmed/25909590
http://dx.doi.org/10.1371/journal.pone.0124936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409305/
https://www.ncbi.nlm.nih.gov/pubmed/25909590
http://dx.doi.org/10.1371/journal.pone.0124936

Ejemplares similares