Cargando…

IL-4 Up-Regulates MiR-21 and the MiRNAs Hosted in the CLCN5 Gene in Chronic Lymphocytic Leukemia

Interleukin 4 (IL-4) induces B-cell differentiation and survival of chronic lymphocytic leukemia (CLL) cells. MicroRNAs (miRNAs) regulate mRNA and protein expression, and several miRNAs, deregulated in CLL, might play roles as oncogenes or tumor suppressors. We have studied the miRNA profile of CLL,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruiz-Lafuente, Natalia, Alcaraz-García, María-José, Sebastián-Ruiz, Silvia, García-Serna, Azahara-María, Gómez-Espuch, Joaquín, Moraleda, José-María, Minguela, Alfredo, García-Alonso, Ana-María, Parrado, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409305/ https://www.ncbi.nlm.nih.gov/pubmed/25909590 http://dx.doi.org/10.1371/journal.pone.0124936

Ejemplares similares

The Gene Expression Response of Chronic Lymphocytic Leukemia Cells to IL-4 Is Specific, Depends on ZAP-70 Status and Is Differentially Affected by an NFκB Inhibitor
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2014)

Dock10, a Cdc42 and Rac1 GEF, induces loss of elongation, filopodia, and ruffles in cervical cancer epithelial HeLa cells
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2015)

Variable Distribution of DOCK-D Proteins between Cytosol and Nucleoplasm in Cell Lines, Effect of Interleukin-4 on DOCK10 in B-Cell Lymphoid Neoplasms, and Validation of a New DOCK10 Antiserum for Immunofluorescence Studies
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2021)

DOCK9 induces membrane ruffles and Rac1 activity in cancer HeLa epithelial cells
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2018)

The role of DOCK10 in the regulation of the transcriptome and aging
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2019)

The transcriptional response of mouse spleen B cells to IL-4: Comparison to the response of human peripheral blood B cells
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2018)

Genetic Variants in MiRNA Processing Genes and Pre-MiRNAs Are Associated with the Risk of Chronic Lymphocytic Leukemia
por: Martin-Guerrero, Idoia, et al.
Publicado: (2015)

miRNA in situ hybridization in circulating tumor cells - MishCTC
por: Ortega, Francisco G., et al.
Publicado: (2015)

Are miRNA-103, miRNA-107 and miRNA-122 Involved in the Prevention of Liver Steatosis Induced by Resveratrol?
por: Gracia, Ana, et al.
Publicado: (2017)

Carbon nanodot–based electrogenerated chemiluminescence biosensor for miRNA-21 detection
por: Gutiérrez-Gálvez, Laura, et al.
Publicado: (2021)

Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions
por: Muñoz-San Martín, María, et al.
Publicado: (2019)

Intestinal Lipid Metabolism Genes Regulated by miRNAs
por: Ruiz-Roso, María Belén, et al.
Publicado: (2020)

Detection of miRNA cancer biomarkers using light activated Molecular Beacons
por: Gonçalves, Odete Sofia Lopes, et al.
Publicado: (2019)

Clinical significance of the expression of miRNA-21, miRNA-31 and miRNA-let7 in patients with lung cancer
por: Wang, Sheng, et al.
Publicado: (2019)

Evaluation of miRNA-7, miRNA-10 and miRNA-21 as diagnostic non-invasive biomarkers of hepatocellular carcinoma
por: Elabd, Walaa K., et al.
Publicado: (2023)

Use of Mature miRNA Strand Selection in miRNAs Families in Cervical Cancer Development
por: Granados-López, Angelica Judith, et al.
Publicado: (2017)

miRNAs in Lymphocytic Leukaemias—The miRror of Drug Resistance
por: Sbirkov, Yordan, et al.
Publicado: (2022)

Visual analytics identifies key miRNAs for differentiating peripancreatic paraganglioma and pancreatic neuroendocrine tumors
por: Enguita, Jose María, et al.
Publicado: (2023)

Circulating miRNAs as diagnostic biomarkers for adolescent idiopathic scoliosis
por: García-Giménez, José Luis, et al.
Publicado: (2018)

Up-regulation of plasma miRNA-21 and miRNA-422a in postmenopausal osteoporosis
por: Mohammadisima, Neda, et al.
Publicado: (2023)

The Type I IFN-Induced miRNA, miR-21
por: Yang, Chuan He, et al.
Publicado: (2015)

Potential plasma biomarkers: miRNA-29c, miRNA-21, and miRNA-155 in clinical progression of Hepatocellular Carcinoma patients
por: Ratnasari, Neneng, et al.
Publicado: (2022)

Characterization and discovery of miRNA and miRNA targets from apomictic and sexual genotypes of Eragrostis curvula
por: Garbus, Ingrid, et al.
Publicado: (2019)

Novel Molecular Characterization of Colorectal Primary Tumors Based on miRNAs
por: Conde, Elisa, et al.
Publicado: (2019)

SNPs in bone-related miRNAs are associated with the osteoporotic phenotype
por: De-Ugarte, Laura, et al.
Publicado: (2017)

Introns of plant pri-miRNAs enhance miRNA biogenesis
por: Bielewicz, Dawid, et al.
Publicado: (2013)

Selective miRNA inhibition in CD8(+) cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses
por: Madrid-Elena, Nadia, et al.
Publicado: (2022)

miRNA miR-21 Is Largely Dispensable for Intrathymic T-Cell Development
por: Kunze-Schumacher, Heike, et al.
Publicado: (2018)

Dynamics of miRNA driven feed-forward loop depends upon miRNA action mechanisms
por: Duk, Maria A, et al.
Publicado: (2014)

MiRNA and Exosomal miRNA as New Biomarkers Useful to Phenotyping Severe Asthma
por: Soccio, Piera, et al.
Publicado: (2023)

Identification of Chloride Channels CLCN3 and CLCN5 Mediating the Excitatory Cl(−) Currents Activated by Sphingosine-1-Phosphate in Sensory Neurons
por: Qi, Yanmei, et al.
Publicado: (2018)

Differential Expression of miRNAs in Trichloroethene-Mediated Inflammatory/Autoimmune Response and Its Modulation by Sulforaphane: Delineating the Role of miRNA-21 and miRNA-690
por: Banerjee, Nivedita, et al.
Publicado: (2022)

The role of MiRNA-21 in gliomas: Hope for a novel therapeutic intervention?
por: Aloizou, Athina-Maria, et al.
Publicado: (2020)

Discovery of miRNAs and Their Corresponding miRNA Genes in Atlantic Cod (Gadus morhua): Use of Stable miRNAs as Reference Genes Reveals Subgroups of miRNAs That Are Highly Expressed in Particular Organs
por: Andreassen, Rune, et al.
Publicado: (2016)

Secreted and Tissue miRNAs as Diagnosis Biomarkers of Malignant Pleural Mesothelioma
por: Martínez-Rivera, Vanessa, et al.
Publicado: (2018)

Intestinal miRNAs regulated in response to dietary lipids
por: Gil-Zamorano, Judit, et al.
Publicado: (2020)

The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family
por: Perdas, Ewelina, et al.
Publicado: (2016)

Interplay of Walnut Consumption, Changes in Circulating miRNAs and Reduction in LDL-Cholesterol in Elders
por: Gil-Zamorano, Judit, et al.
Publicado: (2022)

miRNAs expression of oral squamous cell carcinoma patients: Validation of two putative biomarkers
por: Chamorro Petronacci, Cintia Micaela, et al.
Publicado: (2019)

miRNAs as radio‐response biomarkers for breast cancer stem cells
por: Griñán‐Lisón, Carmen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vcmcnbvtvffv414r4upqaufsll