Glucocorticoids Distinctively Modulate the CFTR Channel with Possible Implications in Lung Development and Transition into Extrauterine Life

During fetal development, the lung is filled with fluid that is secreted by an active Cl- transport promoting lung growth. The basolateral Na(+),K(+),2Cl(-) cotransporter (NKCC1) participates in Cl(-) secretion. The apical Cl(-) channels responsible for secretion are unknown but studies suggest an i...

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Detalles Bibliográficos
Autores principales: Laube, Mandy, Bossmann, Miriam, Thome, Ulrich H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409322/
https://www.ncbi.nlm.nih.gov/pubmed/25910246
http://dx.doi.org/10.1371/journal.pone.0124833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409322/
https://www.ncbi.nlm.nih.gov/pubmed/25910246
http://dx.doi.org/10.1371/journal.pone.0124833

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